Compatibility failures usually come down to three causes: a mod that has not caught up with the current game build, a missing framework, or two mods rewriting the same asset. Read the compatibility markers first, then the dependency list.
When the game crashes, the SMAPI console shows the last mod loaded before the failure. Disable that mod and repeat instead of reinstalling everything, and test on a copy of the save so the worst case costs a backup rather than a farm.